A new locus for Multiple Self-healing Palmoplantar Carcinoma

Mamaï O, Boussofara L, Denguezli M, Escande-Beillard N, Kraeim W, Merriman B, Ben Charfeddine I, Stevanin G, Bouraoui S, Amara A, Mili A, Nouira R, H’mida D, Sriha B, Gribaa M, Saad A, Reversade B.

Multiple Self-healing Palmoplantar Carcinoma (MSPC): a familial predisposition to skin cancer with primary palmoplantar and conjunctival lesions.

J Invest Dermatol 2014 (advance online July 22).

LINK: http://www.nature.com/jid/journal/vaop/naam/abs/jid2014311a.html

We describe here, in a five-generation Tunisian family comprising 27 affected individuals with
autosomal dominant transmission of palmoplantar keratoacanthomass, an unreported syndrome which we have
named: Multiple Self-healing Palmoplantar Carcinoma (MSPC). We mapped the responsible gene to chromosome 17p


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